A study evaluates probable ketoconazole-induced hepatopathy in dogs. Ketoconazole is utilized commonly in dogs at a dose of 10 mg/kg/day to manage cutaneous Malassezia infections. Ketoconazole has been withdrawn from the human pharmaceutical market in Europe and Australia, and has been designated for “restrictive use” only in North America since 2013 due to the potential for this drug to cause severe hepatotoxicity. As well as its anti-yeast activity, ketoconazole is also known to be...

In this Scientific Snapshot, Dr. Geoffrey Truchetti explains the veterinary therapeutic decision cascade to support the responsible use of medications when prescribing drugs to patients. He also examines the appropriate use of compounded products as well as the use of the decision cascade in small animal anesthesia and analgesia.

A study evaluates the occurrence of lesions of endodontic origin in dogs suffering from uncomplicated dental fractures. Fractured teeth are a common occurrence in our canine patients. Studies have revealed that about 25% of dogs will suffer a dental fracture during their lifetime. Common causes of tooth fracture include chewing inappropriate items, fights with other dogs, falls from a height, and blunt trauma. The maxillary fourth premolar is a tooth that is especially susceptible to injury;...

In this Scientific Snapshot, Dr. Jason Stull and Dr. Michelle Evason discuss a recent cross-sectional study they conducted on canine leptospirosis in Canada. During this video, they explain why they chose to investigate this particular research area and share the key findings and data they collected throughout this study. They also discuss how veterinary practitioners can use these findings to help them better prepare to address this daunting disease especially in the fall season, as this...

Dr. Tara Edwards, a veterinary pain practitioner through the International Veterinary Academy of Pain Management, reviews the American Animal Hospital Association’s most recent Pain Management Guidelines for Dogs and Cats. She summarizes updates from the 2015 guidelines and discusses behavioural signs and changes that can help with pain recognition. She provides examples of validated Clinical Metrology Instruments used for screening, diagnosing and monitoring pain over time. She reviews flow...

Dr. Charlie Pye, a board-certified veterinary dermatologist currently practicing at the Atlantic Veterinary College in Prince Edward Island, shares best practices in treatment and management of otitis externa. She provides an overview of primary, secondary, predisposing and perpetuating factors involved in otitis development. She reviews appropriate treatment options based on cytology findings. She also provides answers to common questions, such as when to perform a deep ear flush or a...

A study evaluates the chances of surviving to discharge in cats with uroabdomen. Uroabdomen in cats can occur secondary to vehicular trauma, other blunt trauma, and urinary tract obstruction. It can also be iatrogenic (cystocentesis or rupture during palpation), or due to other less common scenarios. The most common source of urine within the abdomen is secondary to bladder rupture, but urethral injuries can also be a cause. Due to the smaller diameter of the male urethra, leading to less...

Monitoring blood pressure in feline patients can be challenging in clinical practice. In this second video on feline hypertension, Dr. Kelly St. Denis shares her tips and tricks with Dr. Karren Prost. She provides practical guidance on how to reduce the risk of situational hypertension and false positive diagnoses, avoid stressors in the examination room and account for anti-anxiety medications in readings. Dr. St. Denis advises on how to incorporate blood pressure monitoring in busy clinical...

Many feline hypertensive patients remain undiagnosed and undertreated. Dr. Kelly St. Denis shares her blood pressure monitoring recommendations with Dr. Karren Prost, to help identify these patients and prevent irreversible target organ damage. Dr. St. Denis reviews areas of target organ damage associated with hypertension and predisposing conditions and medications. She also highlights common clinical situations that warrant blood pressure monitoring, and discusses the optimal frequency of...