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L'utilisation de SGLT2i : un nouveau médicament oral pour le diabète chez le chat
Présenté par Ellen N. Behrend, Ellen N. Behrend, D.M.V., Ph. D., Dipl. ACVIM (médecine interne des animaux de compagnie)
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L'utilisation de SGLT2i : un nouveau médicament oral pour le diabète chez le chat
Nom
Prénom
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Nom de famille
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Numéro de permis
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Province où se situe votre clinique
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Courriel
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Questions
1. Sodium-glucose cotransporter-2 (SGLT-2) is responsible for reabsorbing what percentage of glucose from renal tubules?
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10%
30%
70%
90%
2. What is the main location of sodium-glucose cotransporter 1 (SGLT-1)?
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Intestines
Liver
Muscle
Kidneys
3. What is glucose toxicity?
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Occurrence of polyuria and polydipsia (PU/PD) and polyphagia due to high blood glucose concentrations
Ability of high blood glucose concentrations to suppress insulin secretion
Ability of high blood glucose concentrations to cause vomiting
Ability of high blood glucose concentrations to cause ketoacidosis
4. The definition of euglycemic diabetic ketoacidosis (EDKA) is the presence of DKA with a blood glucose concentration of:
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<350 mg/dL (19.4 mmol/L)
<250 mg/dL (13.9 mmol/L)
<150 mg/dL (8.3 mmol/L)
<100 mg/dL (5.6 mmol/L)
5. How is euglycemic DKA treated?
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Immediate glucose infusion and delayed treatment with short-acting insulin
Delayed glucose infusion and immediate treatment with short-acting insulin
Immediate glucose infusion and immediate treatment with short-acting insulin
Immediate glucose infusion and immediate treatment with an intermediate-acting insulin
6. What type of diabetes is thought to be most common in cats?
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Type I diabetes
Type 2 diabetes
Diabetes secondary to pancreatitis
Diabetes secondary to hyperthyroidism
7. True or False. When using an SGLT2 inhibitor in a diabetic cat, it is important to pair feeding with drug administration.
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True
False
8. Which of the following is a contraindication to using an SGLT2 inhibitor?
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Hypocalcemia
Blood ketone concentrations of 0–1 mmol/L
Hyperthyroidism
Urinary tract infection
Cachexia
9. True or False. Measuring ketones in serum using a urine dipstick is a more sensitive test for ketosis than measuring ketones in urine using a urine dipstick.
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True
False
10. True or False. Use of an SGLT2 inhibitor in a cat with hypersomatotropism/acromegaly is recommended as there is a good chance (70%) the cat will respond to this medication.
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True
False
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