CommuniVET™ | A pain-free future – Addressing common myths and…

Présenté par Karol A. Mathews, D.M.V., D.V.Sc. (chirurgie), Dipl. ACVECC

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Questions

1. With respect to the safety and efficacy profile of veterinary licensed COXIBs versus non-COXIBs, which one of the following statements is false? *

Recently published data suggests a preferential safety and/or efficacy profile for veterinary licensed non-COXIBs vs COXIBs

While prostaglandins (Pg) derived from COX-2 are the primary mediators of pain and inflammation, Pgs from COX-1 also play a role

Modifying the upregulation of COX1 & 2 derived Pg in the CNS plays a significant role in an NSAIDs analgesic efficacy

Evidence-based medicine clearly supports a superior safety and efficacy profile of veterinary COXIBs vs non-COXIBs

2. When used per label, which of the following statements is true regarding risk of NSAIDs nephrotoxicity to dogs and cats? *

In general, when used per label, the practitioner should feel comfortable in product safety and efficacy profile

Information on the product label provides suggestive rather than definitive information as to product use

Idiosyncratic reactions happen commonly with veterinary licensed NSAIDs regardless of label guidance

Various resources (e.g., veterinary textbook and/or online veterinary websites) provide more relevant data to analgesic product use and should be followed rather than product label

3. Tramadol’s mode of action, makes it an excellent stand-alone analgesic in dogs – true or false? *

True

False

4. Which of the following statements is correct? *

The use of analgesics can be delayed until 24 hours after surgery as the anesthetic agents used provide good 24 hour analgesic effect

When dosing an obese animal, it should be based on ideal rather than actual body weight. Normal and underweight animals should be dosed based on actual weight

All veterinary licensed NSAIDs should not be used pre-emptively due to the risk of inducing bleeding

Post-operative pain management should be used sparingly to avoid the masking of patient decline and subsequent delayed response

5. Based on pediatric ( <4 months) physiology, which of the following statements is true regarding pain management? *

NSAIDs can be given safely from birth onwards when an anti-inflammatory/analgesic is required

Neural physiology indicates that pediatric animals do not perceive pain as adults do and so analgesics are not required for surgical intervention or injury management

Poorly treated pain in the pediatric animal can heighten the sensation of pain in adulthood

Pediatric animals should be fasted for both food and water for 12 hours prior to an anesthetic due to increased risk of aspiration